«The pathophysiological processes of neurodegenerative diseases begin years before diagnosis. However, pre-diagnostic changes in cognition and physical function are poorly understood, especially in sporadic neurodegenerative disease.»

«There was evidence for pre-diagnostic cognitive impairment and decline with time, particularly in AD. Pre-diagnostic functional impairment and decline were observed in multiple diseases.»

Article written by David J. Whiteside,Frank H. Hezemans,Duncan Street,James B. Rowe,Timothy Rittman



Alzeimer’s Association