Summary
Researchers at Anglia Ruskin University in the UK have made a breakthrough in treating age-related macular degeneration (AMD), a leading cause of blindness in developed countries. They used 3D nanotechnology to grow human retinal cells successfully, specifically focusing on the retinal pigment epithelial (RPE) cells. In AMD, the macula, responsible for sharp, central vision, deteriorates, leading to vision loss.
The researchers employed electrospinning, a process that creates a 3D nanofibrous scaffold to support the growth of RPE cells. They coated the scaffold with an anti-inflammatory substance to ensure healthy cell growth without triggering an immune response. The experiment demonstrated enhanced growth, differentiation, and functionality of RPE cells in the 3D environment provided by the scaffold.
This novel technique shows great promise in treating AMD, and the researchers are now exploring ways to transplant these cultivated cells into the human eye. If successful, this advancement could offer a new and effective approach to address sight conditions like AMD, potentially revolutionizing the treatment of this debilitating disease.
Article written by Paul McClure
30/07/2023
Source:
New Atlas
https://newatlas.com/medical/retinal-cells-grown-in-3d-electrospun-scaffold