Researchers at the University of Queensland’s Australian Institute for Bioengineering and Nanotechnology (AIBN) have developed UQ-Surf, a pioneering microfluidics platform that could revolutionise regenerative medicine and tissue engineering. This innovative system enables the high-throughput production of smart microgels, tiny, temperature-sensitive carriers for living biological materials.
Microfluidics allows for precise control over fluid dynamics at the microscale, making UQ-Surf ideal for generating thousands of uniform microgel droplets per minute. These droplets serve as miniaturised environments for cells, biomolecules, or therapeutic agents, and can be tuned simply by adjusting temperature, no harsh chemicals or solvents required.
UQ-Surf overcomes common limitations in microgel fabrication, such as cytotoxicity from chemical demulsifiers, offering a safer and more scalable solution for clinical use. Its ability to encapsulate and release payloads on demand makes it suitable for targeted drug delivery and 3D in vitro tissue modelling.
In tissue engineering, the platform could help develop bioactive scaffolds that promote cell growth and tissue integration. By supporting the controlled release of growth factors or stem cells, UQ-Surf paves the way for more effective therapies for complex medical conditions.
With its patented design and demonstrated proof of concept, UQ-Surf is poised to drive innovation in biomedical science and industrial-scale applications alike.
Article written by Alita Sharon
21/06/2025
Source:
Open Govasia
https://opengovasia.com/2025/06/21/australia-uq-pioneers-smart-microgels-for-medical-use/