Researchers at Rice University have developed a new drug delivery technology called PULSED, which stands for “Particles Uniformly Liquified and Sealed to Encapsulate Drugs”.
The technology uses tiny cylindrical microparticles made of the polymer PLGA that can be filled with a drug, sealed and injected into a patient with a standard hypodermic needle. By tweaking how they made the polymer, the team found they could control how quickly the microparticles dissolved and released their drugs, meaning drug makers could space out when a medication is released in the body over very long time periods, just by including a mix of microparticles that dissolve at different speeds.
The new technology could improve the treatment of chronic diseases by ensuring patients never miss a dose of their prescription medication, and could even help make chemotherapy more effective and reduce its side effects by delivering a prolonged, concentrated dose of the drugs exactly where they are needed.
Article written by Kristin Houser